Closing the loop in child TB contact management: completion of TB preventive therapy outcomes in western Kenya

Author:

Amisi James A,Carter E Jane,Masini Enos,Szkwarko DariaORCID

Abstract

SettingChildren especially those <5 years of age exposed to pulmonary tuberculosis (TB) are at a high risk of severe TB disease and death. Isoniazid preventive therapy (IPT) has been shown to decrease disease progression by up to 90%. Kenya, a high TB burden country experiences numerous operational challenges that limit implementation of TB preventive services. IPT completion in child contacts is not routinely reported in Kenya.ObjectiveThis study aims to review the child contact management (CCM) cascade and present IPT outcomes across 10 clinics in western Kenya.DesignA retrospective chart review of programmatic data of a TB Reach-funded active, clinic-based CCM strategy.ResultsOf 553 child contacts screened, 231 (42%) were reported symptomatic. 74 (13%) of the child contacts were diagnosed with active TB disease. Of those eligible for IPT, 427 (90%) initiated IPT according to TB REACH project data while 249 (58%) were recorded in the IPT register with 49 (11%) recorded as a transfer to other facilities. Of the 249 recorded in the IPT register, 205 (82%) were documented to complete therapy (48% of project initiation children).ConclusionOur evaluation shows gaps in the routine CCM care cascade related to completeness of documentation that require further programmatic monitoring and evaluation to improve CCM outcomes.

Funder

National Institute of General Medical Sciences

Thrasher Research Fund

University of Massachusetts Office of Global Health

Stop TB Partnership TB Reach Initiative

Publisher

BMJ

Subject

General Medicine

Reference17 articles.

1. World Health Organization . Global tuberculosis report 2019. Geneva: WHO, 2019. https://apps.who.int/iris/bitstream/handle/10665/329368/9789241565714-eng.pdf?ua=1

2. The natural history of childhood intra-thoracic tuberculosis: a critical review of literature from the pre-chemotherapy era;Marais;Int J Tuberc Lung Dis,2004

3. Prevalence and risk factors for transmission of infection among children in household contact with adults having pulmonary tuberculosis

4. World Health Organization . Guidance for national tuberculosis programmes on the management of tuberculosis in children second edition, 2014. Available: http://apps.who.int/medicinedocs/documents/s21535en/s21535en.pdf [Accessed 30 Dec 2016].

5. Preventive Effects of Isoniazid in the Treatment of Primary Tuberculosis in Children

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