Differences in birth weight between immigrants’ and natives’ children in Europe and Australia: a LifeCycle comparative observational cohort study

Author:

Florian SandraORCID,Ichou Mathieu,Panico Lidia,Pinel-Jacquemin Stéphanie,Vrijkotte Tanja G M,Harskamp-van Ginkel Margreet WORCID,Huang Rae-Chi,Carson JennieORCID,Rodriguez Loreto Santa Marina,Subiza-Pérez Mikel,Vrijheid Martine,Fernández-Barrés Sílvia,Yang Tiffany CORCID,Wright JohnORCID,Corpeleijn Eva,Cardol Marloes,Isaevska ElenaORCID,Moccia Chiara,Kooijman Marjolein N,Voerman Ellis,Jaddoe Vincent,Welten Marieke,Spada Elena,Rebagliato Marisa,Beneito Andrea,Ronfani Luca,Charles Marie-Aline

Abstract

ObjectiveResearch on adults has identified an immigrant health advantage, known as the ‘immigrant health paradox’, by which migrants exhibit better health outcomes than natives. Is this health advantage transferred from parents to children in the form of higher birth weight relative to children of natives?SettingWestern Europe and Australia.ParticipantsWe use data from nine birth cohorts participating in the LifeCycle Project, including five studies with large samples of immigrants’ children: Etude Longitudinale Française depuis l’Enfance—France (N=12 494), the Raine Study—Australia (N=2283), Born in Bradford—UK (N=4132), Amsterdam Born Children and their Development study—Netherlands (N=4030) and the Generation R study—Netherlands (N=4877). We include male and female babies born to immigrant and native parents.Primary and secondary outcome measuresThe primary outcome is birth weight measured in grams. Different specifications were tested: birth weight as a continuous variable including all births (DV1), the same variable but excluding babies born with over 4500 g (DV2), low birth weight as a 0–1 binary variable (1=birth weight below 2500 g) (DV3). Results using these three measures were similar, only results using DV1 are presented. Parental migration status is measured in four categories: both parents natives, both born abroad, only mother born abroad and only father born abroad.ResultsTwo patterns in children’s birth weight by parental migration status emerged: higher birth weight among children of immigrants in France (+12 g, p<0.10) and Australia (+40 g, p<0.10) and lower birth weight among children of immigrants in the UK (−82 g, p<0.05) and the Netherlands (−80 g and −73 g, p<0.001) compared with natives’ children. Smoking during pregnancy emerged as a mechanism explaining some of the birth weight gaps between children of immigrants and natives.ConclusionThe immigrant health advantage is not universally transferred to children in the form of higher birth weight in all host countries. Further research should investigate whether this cross-national variation is due to differences in immigrant communities, social and healthcare contexts across host countries.

Funder

UK Economic and Social Science Research Council

UK Medical Research Council

Organization for Health Research and Development

Erasmus Medisch Centrum

EarlyNutrition

Raine Study

British Heart Foundation

National Institute for Health Research ARC Yorkshire and Humber

ATHLETE

Polish Ministry of Science and Higher Education

Institut national de la jeunesse et de l’éducation populaire

Hutchison Whampoa Ld, Hong Kong

National Health and Medical Research Council

Australian National Health and Medical Research Council

Instituto de Salud Carlos III

European Research Council

Women and Infants Research Foundation

Telethon Kids Institute

Seventh Framework Programme

Ministry of Youth and Families NL

CERCA Program

Department of Health of the Basque Government

Murdoch University

Edith Cowan University

Rijksuniversiteit Groningen

Well Baby Clinic Foundation Icare, Noordlease, Paediatric Association of the Netherlands, Youth Health Care Drenthe

Curtin University

University of Western Australia

National Institute for Statistics and Economic Studies

National Institute of Health and Medical Research

Healthway and the Lions Eye Institute in Western Australia

Commonwealth Scientific and Industrial Research Organisation

DEPS, Ministry of Culture

DGPR, Ministry for the Environment

Italian National Center for Disease Prevention and Control

EUCAN-Connect

Generalitat de Catalunya

Centro de Excelencia Severo Ochoa

Ministry of Higher Education and Research

Wellcome Trust

Italian Ministry of Health

Netherlands Organisation for Scientific Research

University of Notre Dame Australia

LifeCycle

Childhood Obesity Project

Direction de la Recherche, des Études, de l'Évaluation et des Statistiques

Spanish Ministry of Science and Innovation

Provincial Government of Gipuzkoa

Horizon 2020 Framework Programme

Raine Medical Research Foundation

Agence Nationale de la Recherche

Ministerie van Volksgezondheid, Welzijn en Sport

French Institute for Demographic Studies

Publisher

BMJ

Subject

General Medicine

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