Hyperuricaemia and associated factors among the oldest-old population in the urban areas of Chengdu, China: a community-based cross-sectional study

Abstract

ObjectivesTo investigate the prevalence of hyperuricaemia among the oldest-old persons in Chengdu and identify associated factors to provide information on achieving healthy ageing in China.DesignA community-based cross-sectional study.SettingJinjiang, Qingyang, Longquanyi locating in the southeast, the northwest and the east of Chengdu, respectively, were chosen as the study sites.ParticipantsA representative sample of 1391 people aged over 80 years were enrolled from September 2015 to June 2016, and 106 participants were excluded due to missing information. Thus, a total of 1285 participants were analysed in this study.Outcome measuresHyperuricaemia was defined as serum uric acid >420 µmol/L in men or serum uric acid >360 µmol/L in women. A univariable logistic regression model and a multivariable logistic regression model were used to estimate the ORs and 95% CI to explore the associated risk factors of hyperuricaemia.ResultsThe overall prevalence of hyperuricaemia among the oldest-old was 29.6%. There was no significant sex difference in the prevalence of hyperuricaemia, 29.1% in men vs 30.0% in women (p>0.05). Hyperlipidaemia and overweight were associated with the risk of hyperuricaemia both in men (OR 1.86; 95% CI 1.27 to 2.72; OR 2.44; 95% CI 1.42 to 4.19) and in women (OR 1.78; 95% CI 1.23 to 2.58; OR 2.95; 95% CI 1.89 to 4.61). Additionally, diabetes mellitus was associated with an increased prevalence of hyperuricaemia only in women (OR 1.99; 95% CI: 1.34 to 2.97).ConclusionThe burden of hyperuricaemia is substantial among the oldest-old population in the urban areas of Chengdu, China.