Comparing asphyxia and unexplained causes of death: a retrospective cohort analysis of sleep-related infant death cases from a state child fatality review programme

Author:

Macdonald MeganORCID,Thompson Daniel,Perry Robin,Brooks Robert

Abstract

ObjectivesTo examine the characteristics and circumstances of infants who died while sleeping or in a sleep environment and compare deaths classified as either unintentional asphyxia or an unexplained cause.DesignA retrospective cohort study.SettingData were extracted from the National Fatality Review Case Reporting System and Florida Vital Statistics databases.ParticipantsData on 778 sleep-related infant deaths occurring from 2014 to 2018 in Florida were analysed.Primary outcome measureCause of death classification as unintentional asphyxia or unexplained.ResultsOverall, 36% (n=276) of sleep-related infant deaths in this study sample were classified as resulting from an unexplained cause compared with unintentional asphyxia. Most infants were reported to be in an adult bed (60%; n=464) and sharing a sleep surface with a person or animal (60%; n=468); less than half (44%; n=343) were reportedly placed to sleep on their back. After controlling for the influence of other independent variables, female sex (adjusted risk ratio: 1.36; 95% CI 1.06 to 1.74) and fully obstructed airway condition (adjusted risk ratio: 0.30; 95% CI 0.18 to 0.50) were associated with an unexplained cause of death.ConclusionsThe results of this analysis indicate that sleep environment hazards remain prevalent among infants who die suddenly and unexpectedly, regardless of the cause of death determination. While significant differences were observed for some factors, in many others the distributions of both demographic and incident characteristics were similar between unexplained deaths and those resulting from asphyxia. The results of this study support growing evidence that unsafe sleep environments contribute to all forms of sudden unexpected infant death, underscoring the need for standardising cause of death determination practices and promoting consistent, high-quality forensic investigations to accurately explain, monitor and prevent these deaths.

Funder

Maternal and Child Health Bureau

Publisher

BMJ

Subject

General Medicine

Reference23 articles.

1. United States Department of Health and Human Services (US DHHS) CoDCaPC, National Center for Health Statistics (NCHS), Division of Vital Statistics (DVS) . Linked birth / infant death records 2007-2017, as compiled from data provided by the 57 vital statistics jurisdictions through the vital statistics cooperative program, on CDC wonder on-line database 2019. Available: http://wonder.cdc.gov/lbd-current.html [Accessed 03 Sep 2019].

2. Centers for Disease Control and Prevention (CDC) DoRH . National Center for Chronic Disease Prevention and Health Promotion Sudden Unexpected Infant Death and Sudden Infant Death Syndrome 2018. Available: https://www.cdc.gov/sids/about/index.htm?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fsids%2FAboutSUIDandSIDS.htm [Accessed 03 Oct 2019].

3. Task Force On Sudden Infant Death S . SIDS and other sleep-related infant deaths: updated 2016 recommendations for a safe infant sleeping environment. Pediatrics 2016;138.doi:10.1542/peds.2016-2938

4. Sids and other sleep-related infant deaths: evidence base for 2016 updated recommendations for a safe infant sleeping environment;Moon;Pediatrics,2016

5. Variations in cause-of-death determination for sudden unexpected infant deaths;Shapiro-Mendoza;Pediatrics,2017

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