Risk of recurrent corneal erosion in patients with diabetes mellitus in Taiwan: a population-based cohort study

Author:

Jan Ren-LongORCID,Tai Ming-Cheng,Ho Chung-HanORCID,Chu Chin-Chen,Wang Jhi-Joung,Tseng Sung-Huei,Chang Yuh-ShinORCID

Abstract

ObjectiveTo investigate the risk of recurrent corneal erosion (RCE) in patients with diabetes mellitus (DM).Design, setting and participantsThis retrospective, nationwide, matched cohort study included 239 854 patients with DM recruited between 2003 and 2005 from the Longitudinal Cohort of Diabetes Patients database. The control group included the same number of age-matched and sex-matched patients without DM selected from the Taiwan Longitudinal Health Insurance Database, 2000. Data for each patient were collected from the index date until December 2013.Main outcomes and measuresThe incidence and risk of RCE were compared between the two groups. Cox proportional hazards regression was used to calculate the HR for RCE after adjustment for potential confounders. The cumulative RCE incidence rate was calculated using Kaplan–Meier analysis.ResultsIn total, 1236 patients with DM and 884 controls developed RCE during the follow-up period, resulting in an incidence rate of RCE in patients with DM (5.87/10 000 person-years (PY)) higher than that in the controls (4.23/10 000 PY). After adjustment for potential confounders, including hypertension, hyperlipidaemia, chronic renal disease and keratoconjunctivitis sicca, patients with DM were 1.35 times (95% CI, 1.24 to 1.48) more likely to develop RCE than the total sample cohort.ConclusionsDM increases the risk of RCE, which is an interdisciplinary issue. Therefore, close collaboration between endocrinologists and ophthalmologists is important in managing RCE following DM.

Publisher

BMJ

Subject

General Medicine

Reference38 articles.

1. Diabetes

2. Eclectic ocular comorbidities and systemic diseases with eye involvement: a review;Pinazo-Durán;Biomed Res Int,2016

3. Pathogenesis, clinical features and management of recurrent corneal erosions

4. Recurrent Corneal Erosion Syndrome

5. Recurrent corneal erosion: pathogenesis and therapy;Kenyon;Int Ophthalmol Clin,1979

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3