Phenytoin impairs the bioavailability of dexamethasone in neurological and neurosurgical patients.

Author:

Chalk J B,Ridgeway K,Brophy T,Yelland J D,Eadie M J

Publisher

BMJ

Subject

Psychiatry and Mental health,Neurology (clinical),Surgery

Reference7 articles.

1. Phenytoin and postoperative epilespy. A double-blind study;North, J.B.; RK, Penhall; A, Hanich; DB, Frewin; WB, Taylor;J Neurosurg,1983

2. Effect of diphenylhydantoin on the metabolism of dexamethasone. Mechanism of the abnormal dexamethasone suppression in humans;Jubiz, W.; Meikle, A.W.; Levinson, R.A.; Mizutani, S.; West, C.D.; Tyler, F.H.;New Engl J Med,1970

3. Studies on dexamethasone metabolism in man: effect of diphenylhydantoin;Haque, N.; Thrasher, K.; EE, Jr, Werk; HC, Jr, Knowles; Sholiton, L.J.;J Clin Endocrinol; Bioavailability of oral dexamethasone during high dose steroid therapy in neurological patients,1972

4. High performance liquid chromatographic assay of dexamethasone in plasma and urine;Chain, B.E.; Sadowski, B.; O'Hagan, J.M.; DeWytt, C.N.; Eadie, Bochner F.; M.J.;Ther Drug Monit,1980

5. Marcel Dekker. 1982. 2nd ed.

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