Donor acquired visceral leishmaniasis following liver transplantation

Author:

Dhaliwal AmritpalORCID,Chauhan Abhishek,Aggarwal Dinesh,Davda Pretin,David Miruna,Amel-Kashipaz Rasoul,Brown Rachel,Dedicoat Martin,Clark Fiona,Shah Tahir,Elsharkawy Ahmed MohamedORCID,Ushiro-Lumb Ines,Chiodini Peter,El-Sherif Omar,Armstrong Matthew,Ferguson James W

Abstract

Patients who undergo solid organ transplantation are at risk of opportunistic infection associated with immunosuppression. We report a case of confirmed donor derived visceral leishmaniasis (VL), in a patient following liver transplantation causing fever and pancytopenia. The diagnosis was confirmed by bone marrow biopsy, with confirmed positive donor serology, with no other route of transmission. To our knowledge, this is the first case report in the United Kingdom and Europe, of confirmed organ donor transmission of VL. This case report highlights an important consideration of donor derived infections, in the context of solid organ transplantation.

Publisher

BMJ

Subject

Gastroenterology,Hepatology

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