EULAR recommendations for intra-articular therapies

Author:

Uson JacquelineORCID,Rodriguez-García Sebastián CruzORCID,Castellanos-Moreira RaulORCID,O'Neill Terence W,Doherty Michael,Boesen Mikael,Pandit Hemant,Möller Parera Ingrid,Vardanyan Valentina,Terslev Lene,Kampen Willm Uwe,D'Agostino Maria-Antonietta,Berenbaum FrancisORCID,Nikiphorou ElenaORCID,Pitsillidou Irene A,de la Torre-Aboki JennyORCID,Carmona LoretoORCID,Naredo Esperanza

Abstract

ObjectivesTo establish evidence-based recommendations to guide health professionals using intra-articular therapies (IAT) in adult patients with peripheral arthropathies.MethodsA multidisciplinary international task force established the objectives, users and scope and the need for background information, including systematic literature reviews) and two surveys addressed to healthcare providers and patients throughout Europe. The evidence was discussed in a face-to-face meeting, recommendations were formulated and subsequently voted for anonymously in a three-round Delphi process to obtain the final agreement. The level of evidence was assigned to each recommendation with the Oxford levels of evidence.ResultsRecommendations focus on practical aspects to guide health professionals before, during and after IAT in adult patients with peripheral arthropathies. Five overarching principles and 11 recommendations were established, addressing issues related to patient information, procedure and setting, accuracy, routine and special aseptic care, safety issues and precautions to be addressed in special populations, efficacy and safety of repeated joint injections, use of local anaesthetics and aftercare.ConclusionWe have developed the first evidence and expert opinion-based recommendations to guide health professionals using IAT. We hope that these recommendations will be included in different educational programmes, used by patient associations and put into practice via scientific societies to help improve uniformity and quality of care when performing IAT in peripheral adult joints.

Funder

EULAR

Publisher

BMJ

Subject

General Biochemistry, Genetics and Molecular Biology,Immunology,Immunology and Allergy,Rheumatology

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