Author:
Rubio Torres D. C.,Cárdenas A.,Riegatorres J. C.,Aguilar Rivera L. R.,Chavarín Argüello B. T.,Galarza-Delgado D. Á.
Abstract
BackgroundAn adequate nutritional status and a balanced diet are essential for a functional immune system, especially in chronic diseases that condition a catabolic state. The increase in adipose tissue and the proinflammatory environment that it generates influences rheumatic diseases.1. This translates to increased disease activity, morbidity and mortality.ObjectivesTo describe body composition and nutritional status alterations in patients with rheumatological diseases in a 3rd level center in northern Mexico.MethodsA prospective observational study was conducted in a third level center in northern Mexico. Anthropometric measurements were made by electrical bioimpedance analysis with the InnerScan TANITA BC-533 equipment (Yesod, S.A de C.V. Japan). Descriptive statistics were performed for categorical variables and measures of central tendency and dispersion were used for quantitative variables.ResultsA total of 1,666 evaluations of 1,218 individual patients were included: 1,098 (90.14%) women and 119 (9.77%) men. The mean age was 50 (±13). The most frequent diagnoses were rheumatoid arthritis 556 (45.64%), systemic lupus erythematosus 164 (13.46%), osteoarthritis 106 (8.7%) and fibromyalgia 48 (3.9%). The means of the anthropometric measurements were weight 69.78. kg (±15.53), height 1.57 m (±.07), percentage of total fat 35.17% (±9.3), percentage of body water 45.15% (±6.42), visceral fat 8.32(±.3.9), kg muscle 41.84 kg (6.4), bone mass 2.35 (±.0.75), metabolic age 50(±13), BMI 28.22(±.6.04), waist circumference 92.85(±.15.38), hip circumference 106.8, (±.12.94) waist-hip ratio 0.87 (±.0.08). A total of 431 (35.38%) patients were overweight, 407 (33.41%) had some degree of obesity, 338 (27.75%) had a normal BMI, and only 41 (3.36%) were underweight. 1,013 (83.16%) patients had low lean mass, 719 (59.03%) had low body water percentage, 680 (55.82%) had high levels of total fat, and 163 (13.38%) had visceral fat; 672 (55.17%) sarcopenic obesity and 320 (26.27%) a metabolic age greater than the chronological age.ConclusionThe nutritional status of rheumatology patients in northern Mexico is inadequate with a high prevalence of obesity, overweight, and low lean mass. Nutritional intervention is of paramount importance in the comprehensive management of patients with rheumatologic diseases.References[1]Scrivo, R., Vasile, M., Müller-Ladner, U., Neumann, E., & Valesini, G. (2013). Rheumatic diseases and obesity: adipocytokines as potential comorbidity biomarkers for cardiovascular diseases. Mediators of inflammation, 2013, 808125.Table 1.Means of electrical bioimpedance analysis.VariableMeanSDWeight, kg69.78(15)BMI, kg/m228.22(6.04)Total fat, %35.17(9.3)Total body water, %45.15(6.42)Visceral fat, kg8.32(3.9)Lean mass, kg41.84(6.4)Bone mass, kg2.35(0.75)Metabolic age, years50(13)Waist circumference92.85(15.38)Hip circumference106.8(12.94)W/H ratio0.87(0.08)BMI: Body mass index. W/H ratio: Waist/Hip ratioDisclosure of InterestsNone declared
Subject
General Biochemistry, Genetics and Molecular Biology,Immunology,Immunology and Allergy,Rheumatology