AB0682 Frequency of sexual dysfunction in systemic sclerosis, Santo Domingo, Dominican Republic

Abstract

BackgroundSystemic sclerosis (SSc) is a systemic autoimmune disease.1 Sexual function has been associated with a high prevalence of dissatisfaction.2,3,4 Various factors have been implicated as causes of impaired sexual function.5 CSFQ-14 (Changes in Sexual Functioning Questionnaire) assesses changes in sexual functioning due to disease and/or treatment in 5 domains with a score range of 14-70; cut-off point indicating sexual dysfunction < 41 men and < 47 women.6ObjectivesTo evaluate the frequency and degree of sexual dysfunction in patients with systemic sclerosis.MethodsProspective, observational, cross-sectional study of the cohort of the Rheumatology service at Hospital Docente Padre Billini. Patients were interviewed in November 2021. Inclusion criteria: > 18 years, diagnosis of SSc by ACR/EULAR 2013 classification criteria, at least 1 sexual relationship. Exclusion criteria: previous diagnosis of another autoimmune disease, depression, diabetes, treatment with antidepressants, antiepileptics, narcotics. Measurement of CSFQ-14, mRSS. Statistical analysis was performed with the Pearson correlation (rp) with p=>0.05. The data was analyzed by SPSS V23.ResultsOf 63 patients, 54 met the inclusion criteria. 100% female, mean age 53 + 15.07 years, mean duration 11.3 years, lSSc 24.1% (13), dSSc 75.9% (41), single 50% (27), married 44.4% (24), widowed 5.6% (3). Frequency of sexual dysfunction 81.5% (44). Domains: pleasure 79.6% (43), desire/interest 37% (20), frequency desire 81.5% (44), arousal 46.3% (25), orgasm/completion 75.9% (41). Correlation CSFQ-14 with mRSS: Pleasure dysfunction: normal mRSS 2.3% (1), mild 23.3% (10), moderate 20.9% (9), severe 32.6% (14), terminal 20.9% (9). Desire/interest dysfunction: mild mRSS 35% (7), moderate 20% (4), severe 35% (7), terminal 10% (2). Frequency desire dysfunction: normal mRSS 2.3% (1), mild 25% (11), moderate 15.7% (12), severe 36.4% (16), terminal 20.5% (9). Arousal dysfunction: normal mRSS 4% (1), mild 16% (4), moderate 16% (4), severe 36% (9), terminal 28% (7). Orgasm/completion dysfunction: normal mRSS 2.4% (1), mild 22% (9), moderate 22% (9), severe 26.8% (11), terminal 26.8% (11). rp=. 065 p> 0.05.ConclusionThe study demonstrated a high frequency of sexual dysfunction in most of the population studied. The desire/frequency dysfunction domain turned out to be the one with the highest presentation, followed by the orgasm/completion domain. A statistically significant linear association between sexual dysfunction and cutaneous activity of the disease was evidenced.References[1]Basta F, Afeltra A, Margiotta DPE. Fatigue in systemic sclerosis: a systematic review. Clin Exp Rheumatol. 2018[2]Heřmánková, B., 2019. Sexual Dysfunction in Patients with Systemic Sclerosis. New Insights into Systemic Sclerosis[3]Gao, R., Qing, P., Sun, X., Zeng, X., Hu, X., Zhang, S., Yang, Y. and Qin, L., 2021. Prevalence of Sexual Dysfunction in People With Systemic Sclerosis and the Associated Risk Factors: A Systematic Review. Sexual Medicine, 9(4), p.100392.[4]Frikha, F., Masmoudi, J., Saidi, N. and Bahloul, Z., 2014. Sexual dysfunction in married women with systemic sclerosis. Pan African Medical Journal, 17.[5]Levis B, Burri A, Hudson M, Baron M, Thombs BD, et al. (2012) Sexual Activity and Impairment in Women with Systemic Sclerosis Compared to Women from a General Population Sample. PLoS ONE 7(12): e52129.[6]Clayton AH, McGarvey EL, Clavet GJ. The Changes in Sexual Functioning Questionnaire (CSFQ): development, reliability, and validity. Psychopharmacol Bull. 1997;33(4):731-45.Disclosure of InterestsNone declared