1. Abnormal Deposits of Iron in Vessel Walls and in the Form of Globules.-Aschoff,7 in 1902, first drew attention to the occurrence of calcium and iron deposits in vessel walls in the brain. Perusini,9 in 1912, in a case of idiocy, made an exhaustive chemical study of certain globules which he found in the brain of his patient. Ellischer 1 described these globules as ' chorea bodies ' (Korperchen), as he found them in a case of chorea gravidarum. This name is most misleading, since these globules occur in many conditions other than chorea, as was shown by Jakowenko 2 and Wollenberg.3 Nevertheless, it is still retained in the German literature on the subject