Dependence of treatment effectiveness in dogs ticke-borreliosis from the time of diagnosis

Abstract

The importance and necessity of confirming the diagnosis of tick-borne borreliosis (Lyme disease) in dogs at the initial stages is due to the possibility of timely prescribing specific treatment and reducing the recovery time of animals. In the conditions of a veterinary clinic in St. Petersburg, tick-borne borreliosis was diagnosed in dogs, taking into account the parasitism of ixodid ticks, erythema at the site of their attachment, depression, lowgrade fever, anorexia, lameness, paraplegia, and confirmed by the PCR. In dogs of one of the experimental groups, after removing the ticks, the Borrelia Test test system was used to detect the pathogen Borrelia burgdorferi. Dogs were treated with tertacycline preparations - "Doxycycline", "Doxyfin" and fluoroquinolones - "Enroflaxocin". It was found that the oral administration of drugs "Doxycycline" and "Doxyfin" to dogs at the rate of 10 mg / kg of animal weight, 1 time per day, for 28 days is equally effective in Lyme disease. The alternation of the use of bacteriostatic antibiotics of the tetracycline series and fluoroquinolones has a greater therapeutic efficacy compared to the use of only drugs of the tetracycline group. The use of drugs "Enroflaxocin" and "Doxycycline" reduced the recovery time of animals to three weeks compared to 28 days when animals were treated only with tetracycline antibiotics. The early timing of the detection of borrelia in ixodid ticks made it possible to timely prescribe treatment to animals. In dogs of this group, it was possible to avoid the development of a severe course of tick-borne borreliosis, accompanied by a long period of fever, the development of signs of anorexia, depression, lameness, and the use of drugs from the fluoroquinolones and tetracyclines groups reduced the recovery time of animals to two weeks