Affiliation:
1. St. Petersburg State University of Veterinary Medicine
Abstract
The results of a study of changes in some laboratory parameters and the use of instrumental research methods for ovarian leiomyoma in dogs are presented using the example of a clinical case. The animal observed increased frequency of urination, episodes of enuresis, and an increase in abdominal volume. It was determined that there are no special morphological changes in the blood associated with leiomyoma, but pronounced lymphopenia of unknown origin was determined. Urine examination also did not reveal significant deviations in its composition. An ultrasound examination revealed a solid formation in the area of the left ovary measuring 15.22*9.80 cm, displaced towards the spleen, hypoechoic, with areas of heterogeneous echogenicity, its contours are unclear. During intraoperative removal of the tumor and its histological examination, a benign formation was revealed - leiomyoma. It is a tumor of diffuse structure, formed by chaotically intertwined, distinctly arranged, large bundles of spindle-shaped cells. Tumor cells are long, elongated, with well-defined eosinophilic cytoplasm, with indistinguishable cell boundaries. The nuclei are medium-sized, elongated, normochromic and lightcolored, with finely dispersed chromatin. Cellular and nuclear polymorphism is weakly expressed, single mitoses are detected. In bundles of tumor cells, a large amount of eosinophilic matrix is detected, visually merging with the eosinophilic cytoplasm of the cells.
Publisher
Saint-Petersburg State University of Veterinary Medicine
Reference11 articles.
1. Gaponova, V. N. Effect of sodium hypochlorite on laboratory and clinical parameters of urine in dogs with chronic kidney disease / V. N. Gaponova, S. P. Kovalev, V. A. Trushkin // Hippology and Veterinary Medicine. – 2016. – No. 4(22). – pp. 97-100.
2. Methods for diagnosing hypertrophic cardiomyopathy in cats / V. A. Trushkin, A. A. Nikitina, S. P. Kovalev [etc.] // Issues of legal regulation in veterinary medicine. – 2021. – No. 4. – P. 86-89.
3. Nikitin, G. S. The use of correlation analysis to determine the direction and quantitative measurement of connections in biometrics (on the example of zoohygienic assessment of feeding broiler chickens with various feeds / G. S. Nikitin, M. G. Nikitina // Practice of using natural scientific methods in applied social and humanitarian research: Collection of materials from a methodological seminar, December 18-19, 2014, Tolyatti, December 18-19, 2014. Volume Part 1. - Tolyatti: Tolyatti State University, 2014. - P. 281-287.
4. Nikitina, A. A. Results of clinical and laboratory studies in a dog with a uterine tumor / A. A. Nikitina, G. S. Nikitin // Legal regulation in veterinary medicine. – 2022. – No. 1. – P. 52-54.
5. The role of clinical and laboratory studies in the diagnosis of chronic renal failure in dogs / S. P. Kovalev, P. S. Kiselenko, V. N. Gaponova [etc.] // Issues of legal regulation in veterinary medicine. – 2018. – No. 4. – P. 129-132.