A Unique Case of Intracranial Amelanotic Melanoma with BRAF V600E Mutation Successfully Treated via Molecular-targeted Therapy
Author:
Affiliation:
1. Department of Neurosurgery and Neuroendovascular Surgery, Hiroshima City Hiroshima Citizens Hospital
2. Department of Diagnostic Pathology, Hiroshima City Hiroshima Citizens Hospital
Publisher
Japan Neurosurgical Society
Subject
Polymers and Plastics,General Environmental Science
Link
https://www.jstage.jst.go.jp/article/nmccrj/10/0/10_2022-0227/_pdf
Reference17 articles.
1. 1) Anonymous: Brain Tumor Registry of Japan (2005-2008). Neurol Med Chir (Tokyo) 57: 9-102, 2017
2. 2) Sloan AE, Nock CJ, Einstein DB: Diagnosis and treatment of melanoma brain metastasis: a literature review. Cancer Control 16: 248-255, 2009
3. 3) Sperduto PW, Jiang W, Brown PD, et al.: Estimating survival in melanoma patients with brain metastases: an update of the graded prognostic assessment for melanoma using molecular markers (melanoma-molGPA). Int J Radiat Oncol Biol Phys 99: 812-816, 2017
4. 4) Saiag P, Robert C, Grob JJ, et al.: Efficacy, safety and factors associated with disease progression in patients with unresectable (stage III) or distant metastatic (stage IV) BRAF V600-mutant melanoma: an open label, non-randomized, phase IIIb study of trametinib in combination with dabrafenib. Eur J Cancer 154: 57-65, 2021
5. 5) Jaimes N, Braun RP, Thomas L, Marghoob AA: Clinical and dermoscopic characteristics of amelanotic melanomas that are not of the nodular subtype. J Eur Acad Dermatol Venereol 26: 591-596, 2012
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1. Comparative Analysis of the Effect of the BRAF Inhibitor Dabrafenib in 2D and 3D Cell Culture Models of Human Metastatic Melanoma Cells;In Vivo;2024
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