Wearable Biosensor Utilizing Chitosan Biopolymer for Uric Acid Monitoring-Reference-Cited by-同舟云学术

Wearable Biosensor Utilizing Chitosan Biopolymer for Uric Acid Monitoring

Published:2023-10-20 Issue:5 Volume:35 Page:1131-1134
ISSN:1883-8049
Container-title:Journal of Robotics and Mechatronics
language:en
Short-container-title:J. Robot. Mechatron.

Author:

Sato Mizuki¹,Kamiyama Tatsuya²,Iitani Kenta³^ORCID,Yano Kazuyoshi⁴,Mitsubayashi Kohji³^ORCID,Arakawa Takahiro¹²^ORCID

Affiliation:

1. Graduate School of Engineering, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan

2. Department of Electric and Electronic Engineering, School of Engineering, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan

3. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-surugadai, Chiyoda-ku, Tokyo 101-0062, Japan

4. Graduate School of Bionics, Computer and Media Sciences, Tokyo University of Technology, 1404-1 Katakura, Hachioji, Tokyo 192-0982, Japan

Abstract

A wearable biosensor was specifically engineered to measure uric acid, a biomarker present at wound sites. This biosensor, fabricated as a disposable and wearable device, was seamlessly integrated onto a polyethylene terephthalate (PET) substrate by utilizing carbon and silver conductive paste as the electrodes. The enzyme uricase was immobilized onto the working electrode by utilizing chitosan, a biocompatible material, to create this biosensor. Notably, the uric acid biosensor fabricated with chitosan showcased exceptional performance metrics, including remarkable output current values and impeccable stability. These findings suggest the prospective utilization of chitosan-based uric acid biosensors for the accurate measurement of uric acid on human skin in future applications.

Funder

Tokyo University of Technology

Publisher

Fuji Technology Press Ltd.

Subject

Electrical and Electronic Engineering,General Computer Science

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