Antipyrine clearance and Metabolite Excretion in Saudi Patients with Non-Alcoholic Chronic Liver Disease

Author:

Ali Hatim A.1,El-Yazigi Adnan1,Sieck Jens O.1,Ali Muhammed A.1,Dossing Martin1,Raines Dale A.1,Saour Jalal1,Ernst Peter1,Khan Bashir1

Affiliation:

1. From the Departments of Medicine (Drs. H. Ali, J. Sieck, Dossing, Saour); Biological and Medical Research (Dr. El-Yazigi, Mr. Raines); Pathology and Laboratory Medicine (Dr. M. Ali); Oncology (Dr. Ernst); and Biomedical Statistics and Scientific Computing (Dr. Khan); King Faisal Specialist Hospital and Research Centre, Riyadh

Publisher

King Faisal Specialist Hospital and Research Centre

Subject

General Medicine

Reference17 articles.

1. Antipyrine as a model drug to study hepatic drug-metabolizing capacity;Poulsen HE;J Hepatol,1988

2. The antipyrine test in clinical pharmacology: conceptions and misconceptions;Vesell ES;Clin Pharmacol Ther,1979

3. Dynamic interactions among host factors that influence antipyrine metabolism: implications for the design and interpretation of studies in ethnic pharmacokinetic variations;Vesell ES;Prog-Clin-Biol-Res,1986

4. Antipyrine metabolism in man: influence of age, alcohol, caffeine and smoking;Vestal RE;Clin Pharmacol Ther,1975

5. Studies on the differential metabolic pathways of antipyrine in man. I. Oral administration of 250 mg, 500 mg and 1000 mg to healthy volunteers;Danhof M;Br J Clin Pharmacol,1979

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