Author:
Gaman Mihnea Alexandru,Epingeac Mirela Elena,Gaman Amelia Maria
Abstract
Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive B-cell non-Hodgkin�s lymphoma. Oxidative stress, defined as an imbalance between the levels of pro-oxidants and the antioxidant defense, is involved in lymphomagenesis via chronic inflammation and is associated with a decrease in circulating levels of high-density lipoprotein (HDL) cholesterol. We evaluated oxidative stress levels in DLBCL patients by FORT (Free Oxygen Radicals Testing) and FORD assays (Free Oxygen Radical Defense), and investigated the relationship between oxidative stress markers and HDL-cholesterol levels. Our results suggest that oxidative stress and decreased levels of HDL-cholesterol might play a role in DLBCL pathogenesis via chronic inflammation.
Subject
General Chemistry,Materials Science (miscellaneous),Materials Chemistry,Process Chemistry and Technology,General Engineering,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Pharmacology, Toxicology and Pharmaceutics
Cited by
22 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献