Calcifediol Concentration vs Circulating Thyrotropin and Free Thyroxine in Human Blood of Postmenopausal Women

Abstract

A total of 55 patients were: G1 of 9 patients, G2 of 23 subjects, and G3 of 23 patients. Similar age and years since menopause was found between the groups. There was no statistical significant difference between the groups regarding these aspects: p-value G1-G2 of 0.67, p-value G1-G3 of 0.72, p-value G2-G3 of 0.47. Similar results were obtained when TSH, FT4 and anti-thyroperoxidase antibodies were analysed between the groups. No TSH-25-OHD correlation reached the statistical significance, neither FT4-25-OHD, TPO-25-OD. P-values between G1 and G2 for TSH, FT4, TPO were 0.23, 0.38, respective 0.7, between G2 and G3 were 0.19, 0.1, 0.35, between G1 and G3 were 0.48, 0.84, respective 0.75. Bone profile analyze based on 25-OHD levels did not identify any statistical significance difference between the mentioned groups (including bone turnover markers).