Applications of Polymers for Tissue Regeneration in Medical Treatment
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Published:2022-12-30
Issue:
Volume:26
Page:238-245
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ISSN:2791-0210
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Container-title:Highlights in Science, Engineering and Technology
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language:
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Short-container-title:HSET
Abstract
Multiple types of damage to human organs can result in dysfunction and incapacity. The importance of tissue repair and regeneration in the medical industry results in high demand for tissue regeneration materials. Since the scaffolds considerably speed up the healing process, the use of tissue engineering scaffolds in the restoration of injured tissues has shown amazing potential. Due to their superior processability and biocompatibility, polymers are frequently used to build three-dimensional scaffolds. However, the main issues that restrict their widespread clinical application are their inadequate mechanical strength and unsuitable degradation rate in the bone regeneration process. Because of their superior mechanical strength, synthetic biodegradable polymer composites are used. In this research, the most frequently used polymers including polycaprolactone (PCL) and gelatine methacrylate (GelMA) were employed to create polymer composite scaffolds. And this research categorized polymer materials for tissue regeneration based on their uses in different human organs and described their physical or chemical properties. The reader is given evaluations of each material as well as prospects.
Publisher
Darcy & Roy Press Co. Ltd.
Reference13 articles.
1. Khan, F. and Tanaka, M., 2017. Designing Smart Biomaterials for Tissue Engineering [J]. International Journal of Molecular Sciences, 19(1), p.17. 2. Gao, J., Ding, X., Yu, X., Chen, X., Zhang, X., Cui, S., Shi, J., Chen, J., Yu, L., Chen, S., and Ding, J., 2020. Cell-Free Bilayered Porous Scaffolds for Osteochondral Regeneration Fabricated by Continuous 3D-Printing Using Nascent Physical Hydrogel as Ink [J]. Advanced Healthcare Materials, 10(3), p.2001404. 3. Raffaele Conte, Anna Di Salle, Francesco Riccitiello, Orsolina Petillo, Gianfranco Peluso, Anna Calarco. Biodegradable polymers in dental tissue engineering and regeneration [J]. AIMS Materials Science, 2018, 5(6): 1073-1101. doi: 10.3934/matersci.2018.6.10732 Main Body 4. Li, Z., Li, S., Yang, J., Ha, Y., Zhang, Q., Zhou, X. and He, C., 2022. 3D bioprinted gelatin/gellan gum-based scaffold with double-crosslinking network for vascularized bone regeneration [J]. Carbohydrate Polymers, 290, p.119469. 5. Liu, D., Nie, W., Li, D., Wang, W., Zheng, L., Zhang, J., Zhang, J., Peng, C., Mo, X. and He, C., 2019. 3D printed PCL/SrHA scaffold for enhanced bone regeneration [J]. Chemical Engineering Journal, 362, pp.269-279.
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