T-VEC for Cancer Therapy: Applications, Limitations, and Potentials

Abstract

Cancer is a great threat to human health, and immunotherapy has become an important means to treat cancer in recent years. Talimogene laherparepvec (T-VEC), as an oncolytic virus, is one of the immunotherapy for melanoma. This article explains its mechanism, and then summarizes its clinical applications, including the effects and safety of monotherapy and combination therapy. Current limitations and potentials of T-VEC are also analyzed, in order to provide guidance for the further development of it and even other oncolytic viruses.