Bipolar disorder(BPD):epidemiological characteristics, current situation and treatment

Abstract

Bipolar disorder (BPD) is a common mental disease. Patients have both depressive symptoms and manic symptoms, which affect the quality of life of patients. At the same time, it can be complicated with somatic symptoms. Patients often feel incompetent, or even commit suicide. BPD has a high misdiagnosis rate, accompanied by high morbidity and mortality, so people should pay more attention to BPD. Many factors may lead to BPD, such as the high recurrence rate of patients in families with high emotional expression; the recovery period of patients with negative life events was prolonged; patients with bad social adaptation and environmental stress have an increased probability of serious emotional symptoms or affective disorders; Patients with irregular life are prone to attack when facing negative life events, but most of them are from heredity or environment. According to the pathogenesis or characteristics of BPD, many epidemiological studies have been carried out clinically, such as family research, adoption research, twins research, etc. the treatment of bipolar disorder, in the maintenance treatment of drugs, There are sufficient evidences that lithium salt are effective for both acute manic episodes and depressive episodes, does not cause manic depressive transition, and long-term use can prevent recurrence, also reduce the suicide rate of patients.