Abstract
Acne has long been recognized as a widespread skin condition, and its prevalence is currently increasing. One of the top 10 epidemics in the world right now, it has a serious psychological toll on its victims. Four interconnected processes, including inflammation, increased sebum production, follicular infundibular hyperkeratosis, and Chlamydia acne growth, make up the disease's complicated pathophysiology. Antibiotics that target P. acnes have been a successful and popular way to treat acne for the past 40 years, even though the pathophysiology of acne is not entirely understood. The emergence of antibiotic resistance, however, is a persistent issue with a variety of negative consequences. Isotretinoin and antiandrogen therapy are frequent therapies for certain of them. This article summarizes the effectiveness and safety of oral antibiotics for acne treatment in recent years as well as some other recent treatment research, operating under the premise that the current domestic and international clinical trials of acne vulgaris are insufficient. The goal is to raise awareness of acne vulgaris.
Publisher
Darcy & Roy Press Co. Ltd.
Reference10 articles.
1. Haoxiang Xu and Huiying Li, “Acne, the Skin Microbiome, and Antibiotic Treatment”, Am J Clin Dermatol. 2019 Jun;20(3):335-344.
2. Hilary Baldwin, “Oral Antibiotic Treatment Options for Acne Vulgaris”, J Clin Aesthet Dermatol. 2020 Sep
3. Janet DuBois MD, Gavin Chun Wei Ong MD, “Patient-Reported Outcomes in Acne Patients With Skin of Color Using Adapalene 0.3%-Benzoyl Peroxide 2.5%: A Prospective Real-World Study”, June 2019 | Volume 18 | Issue 6 | Original Article | 514 | Copyright © June 2019
4. Keisuke Nakase, Sae Aoki, “Characterization of acne patients carrying clindamycin-resistant Cutibacterium acnes: A Japanese multicenter study”, J Dermatol. 2020 Aug;47(8):863-869.
5. Ichiro Kurokawa and Keisuke Nakase, “Recent advances in understanding and managing acne”, F1000Res. 2020 Jul 29;9: F1000 Faculty Rev-792.