How the Gene NRG1, Erbb4, DAOA, and DISC1 Can Affect the Schizophrenia

Abstract

Schizophrenia is a mental disease that affects many people. Up to now, it is still difficult to cure. So, it is important to find the causes of this disease. Genes play an important role in the many cause of schizophrenia. Many researchers have found that the genes NRG1, Erbb4, DAOA, and DISC1 can cause schizophrenia by affecting some structures of the nervous system and directly or indirectly affecting the release of neurotransmitters. Of course, each gene may have a specific pathway leading to the disease. Different genes can also interact with other genes to affect diseases, such as gene NRG1 and Erbb4, gene DAOA and DISC1. This paper summarizes some recent experiments to find the relationship between genes and schizophrenia. Some of the causes of schizophrenia summarized in this paper are important for the development of drugs to treat the disease.