Application of Paclitaxel in Ovarian Cancer and Effect of Different Administration Methods

Abstract

Paclitaxel, which acts on the spindle apparatus to kill cancer cells, as a classic drug for cancer treatment, has attracted people's attention in the application prospect of ovarian cancer. In the aspect of synthesis, currently, paclitaxel is obtained by natural synthesis and artificial synthesis. The yield of natural synthesis is not good. Artificial synthesis has a high conversion rate, but it still needs to reduce the synthesis steps and increase the yield. In terms of drug intake, the side effects of injection can be reduced by oral administration instead of prolonged injection time. As for the side effects of the drug itself, although there are still many side effects caused by the use of taxol to treat ovarian cancer, the effect can be improved by combining it with natural drugs. From the synthesis, medication methods and clinical problems of paclitaxel, the current prospects and problems in the application of paclitaxel were analyzed comprehensively, and the conclusion was drawn that paclitaxel is a drug worth using and expected to be improved at the present stage.