Association of Gut Flora and Short-Chain Fatty Acid Metabolite in Functional Constipation and Regulation of High-Fibre Diet on Them

Abstract

Constipation is one of the most prevalent diseases in the world, and it has a significant impact on the quality of life of people. There are several critical factors associated with constipation, including short-chain fatty acid content and the composition of the gut microbiota. A disorder in any of these factors can cause an abnormal bowel movement and the symptoms of constipation. Diet regulates the gut microbiota and influences the immune system. Recent research suggests that high fibre foods promote the growth and stabilization of the intestinal nerves, as well as an increase in the number of useful bacteria found in the intestines. Fibre deficiency increases the risk of GI distress and contributes to poor gastrointestinal motility. Long-term treatment of constipation is dependent on developing a diet that provides sufficient fibre. A high fibre diet is probably not just essential to manage constipation, but also to lower the risk of developing other chronic illnesses associated with diet. In this paper, the relationship between high fibre diet and microbiota and short chain fatty acids in constipation patients is analyzed.