Evaluation of the structural development potential of receptors based on SARS-CoV-2 infection

Abstract

Since 2019, the coronavirus has posed a huge threat to human health and the environment. Many scholars have since started studying the coronavirus and its branches, including SARS-CoV-2. SARS-CoV-2 is a positive stranded RNA virus composed of four main proteins and several auxiliary proteins that encapsulate genetic material. It mainly mediates virus invasion through the binding of S protein to host cell receptors, determining the tissue and host preference of the virus. ACE2 is a receptor required for SARS-CoV-2 to enter cells, which is consistent with the epidemiological risk of severe diseases observed in Chinese cardiovascular disease and hypertension patients. This article will explore the potential development of SARS-CoV-2 receptor ACE2 in terms of structure.