Brief Description and Application of Microneedle Biosensors

Abstract

In recent years, tremendous advances have been made in microneedle (MN)-based biosensors. MN biosensors have been used as devices for developing non-invasive, continuous monitoring of patient health status due to their painless, non-blood contact characteristics. The development of biosensors based on an integrated microneedle platform for the detection of biomarkers in interstitial fluid is covered in this article. The combination of microneedle platforms with biosensors continues to create new opportunities for non-invasive detection and ongoing monitoring. The classification of MN microneedles and multiple MN biosensors for identifying various bodily fluid components, such as blood glucose, antibiotics, lactate, etc., are presented in this study. It reviews this next generation MN integrated circuit platform and explains the various directions of current MN integrated circuit platform development. These have been combined with electrochemical biosensor integration for quantitative detection of various metabolites, electrolytes, and other substances known to be present in interdermal tissue fluids. Furthermore, this paper explores some of the major issues and potential solutions for this new MN sensing technology.