Author:
dos Santos Souza Marinho Robson,Duro Rodrigo Lopes Sanz,Bellini Caldeira Débora,Galinskas Juliana,Oliveira Mota Mânlio Tasso,Hunter James,Rodrigues Teles Maria da Aparecida,de Pádua Milagres Flávio Augusto,Sobhie Diaz Ricardo,Shinji Kawakubo Fernando,Vasconcelos Komninakis Shirley
Abstract
Abstract
Objective
To perform a molecular screening to detect infections by the mayaro virus and possible coinfections with Chikungunya during an outbreak in the state of Tocantins/Brazil in 2017.
Results
Of a total 102 samples analyzed in this study, 6 cases were identified with simultaneous infection between mayaro and chikungunya viruses (5.88%). In these 6 samples, the mean Cycle threshold (Ct) for CHIKV was 26.87 (SD ± 10.54) and for MAYV was 29.58 (SD ± 6.34). The mayaro sequences generated showed 95–100% identity to other Brazilian sequences of this virus and with other MAYV isolates obtained from human and arthropods in different regions of the world. The remaining samples were detected with CHIKV monoinfection (41 cases), DENV monoinfection (50 cases) and coinfection between CHIKV/DENV (5 cases). We did not detect MAYV monoinfections.
Funder
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Cited by
13 articles.
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