Author:
Nikoubakht Nasim,Faiz Seyed Hamid Reza,Mousavie Seyed Hamzeh,Shafeinia Amineh,Borhani Zonoz Leila
Abstract
Abstract
Objective
We aimed to compare the effect of bupivacaine intraperitoneal with intra-abdominal bicarbonate in reducing postoperative pain in laparoscopic cholecystectomy.
Results
In this double-blind randomized clinical trial study, 58 patients underwent laparoscopic cholecystectomy referred to a hospital in Tehran, Iran (2019), were assigned into three groups: at the end of the surgery, spraying 50 cc of bupivacaine 0.2% through the laparoscopic port; or rinsing the abdomen with 5.7% bicarbonate dissolved in 1000 cc of normal saline; or abdominal lavage with normal saline. Pain of patients was evaluated according to visual analogue scale criteria and means Ramsay score in recovery times, 2, 8 and 24 h and post-operative analgesia satisfaction score at 2 and 24 h were also evaluated. The mean age of range was 44.26 ± 13.13 years, 44 female patients and 14 male patients. The mean Ramsay score in recovery, 2, 8 and 24 h postoperative times was not significantly different among the groups. Comparing post-operative analgesic satisfaction scores in recovery, 2 and 24 h revealed no significant difference among the groups. We found that use of bupivacaine intraperitoneal and intra-abdominal bicarbonate decreased pain after laparoscopic cholecystectomy but the decrease was more in bupivacaine group than bicarbonate group.
Trial Registration: Retrospectively registered, IRCT20180723040570N1; date of registration: 2019-06-24.
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference24 articles.
1. Sinatra R. Causes and consequences of inadequate management of acute pain. Pain Med. 2010;11:1859–71.
2. Rahimzadeh P, Faiz SH, Hoseini M, Mousavie SH, Imani F, Negahi AR. Comparison of intraperitoneal bupivacaine, acetazolamide, and placebo on pain relief after laparoscopic cholecystectomy surgery: a clinical trial. Med J Islam Repub Iran. 2018;13(32):112.
3. Hurley RW, Murphy JD, Wu CL. Acute Postoperative Pain. In: Miller RD, editor. Anesthesia. Philadelphia: Elsevier Saunders; 2015.
4. Wu CL, Fleisher LA. Outcomes research in regional anaesthesia and analgesia. Anesth Analg. 2000;91:1232–42.
5. Liu S, Carpenter RL, Neal JM. Epidural anaesthesia and analgesia their role in postoperative outcome. Anesthesiology. 1995;82:1474–506.
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