A conditional Pax6 depletion study with no morphological effect on the adult mouse corneal epithelium

Author:

Dorà Natalie J.,Manuel Martine,Kleinjan Dirk-Jan,Price David J.,Collinson J. Martin,Hill Robert E.,West John D.ORCID

Funder

Wellcome Trust

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference34 articles.

1. Mort RL, Douvaras P, Morley SD, Dorà N, Hill RE, Collinson JM, West JD. Stem cells and corneal epithelial maintenance: insights from the mouse and other animal models. In: Kubiak JZ, editor. Results Probl Cell Differ, 55, “Mouse development: from oocyte to stem cells”. Berlin: Springer; 2012. p. 357–94.

2. Shaham O, Menuchin Y, Farhy C, Ashery-Padan R. Pax6: a multi-level regulator of ocular development. Prog Retin Eye Res. 2012;31(5):351–76.

3. Hill RE, Favor J, Hogan BLM, Ton CCT, Saunders GF, Hanson IM, Prosser J, Jordan T, Hastie ND, VanHeyningen V. Mouse small eye results from mutations in a paired-like homeobox-containing gene. Nature. 1991;354(6354):522–5.

4. van Raamsdonk CD, Tilghman SM. Dosage requirement and allelic expression of PAX6 during lens placode formation. Development. 2000;127(24):5439–48.

5. Collinson JM, Quinn JC, Buchanan MA, Kaufman MH, Wedden SE, West JD, Hill RE. Primary defects in the lens underlie complex anterior segment abnormalities of the Pax6 heterozygous eye. Proc Natl Acad Sci USA. 2001;98(17):9688–93.

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