Oropouche infection a neglected arbovirus in patients with acute febrile illness from the Peruvian coast

Author:

Martins-Luna Johanna,del Valle-Mendoza JuanaORCID,Silva-Caso Wilmer,Sandoval Isabel,del Valle Luis J.,Palomares-Reyes Carlos,Carrillo-Ng Hugo,Peña-Tuesta Isaac,Aguilar-Luis Miguel Angel

Abstract

Abstract Objective To evaluate the frequency of infection caused by the Oropouche virus (OROV) in 496 patients with acute febrile disease (AFI), whose samples were obtained for the analysis of endemic arboviruses in a previous investigation carried out in 2016. Results OROV was detected in 26.4% (131/496) of serum samples from patients with AFI. Co-infections with Dengue virus (7.3%), Zika virus (1.8%) and Chikungunya (0.2%) were observed. The most common clinical symptoms reported among the patients with OROV infections were headache 85.5% (112/131), myalgia 80.9% (106/131), arthralgia 72.5% (95/131) and loss of appetite 67.9% (89/131). Headache and myalgia were predominant in all age groups. Both OROV infections and co-infections were more frequent in May, June and July corresponding to the dry season of the region.

Funder

CONCYTEC Peru

Bio & Medical Technology Development Program of the National Research Foundation (NRF) funded by the Korean government

Incentive for Research of the Universidad Peruana de Ciencias Aplicadas

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

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