Abstract
Abstract
Objective
It is estimated that 50% to 90% of infants born with (SCA) in sub-Saharan Africa die before 5 years old. Northern Darfur State at western Sudan region has a multiethnic population with a high frequency of sickle cell anaemia, but little about it is published. This study aimed to determine the prevalence of sickle cell anaemia among children admitted to Al Fashir Teaching Hospital in Al Fashir, Northern Darfur State, Sudan.
Results
The prevalence of sickle cell disease by haemoglobin electrophoresis among these 400 children patients was 59 (14.8%). Sickle cell trait patients were 11.3% and Sickle cell disease positive patients were 3.5%. Individuals with SCA have consistently low blood Hb concentration, normal MCV and high mean WBC’s. Individuals with sickle cell trait had haematological parameters near to those of normal individuals.
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference23 articles.
1. Ifeanyi OE, Ochei KC, Nwachukwu BN, Ogechi NB. Sickle cell anaemia: a review. Sch J App Med Sci. 2015;3(6B):2244–52.
2. Modell B, Darlison M, Birgens H, Cario H, Faustino P, Giordano PC. Epidemiology of haemoglobin disorders in Europe: an overview. Scand J Clin Lab Investig. 2007;67(1):39–69.
3. Mulumba LL, Wilson L. Sickle cell disease among children in Africa: an integrative literature review and global recommendations. Int J Afr Nurs Sci. 2015;3:56–64.
4. Sack FN, Njangtang DM, Chemegni BC, Djientcheu VP. Prevalence of sickle cell disease in newborns in the Yaounde Central Hospital. JMR. 2017;3(6):277–9.
5. Macharia AW, Mochamah G, Uyoga S, Ndila CM, Nyutu G, Makale J, et al. The clinical epidemiology of sickle cell anaemia in Africa. Am J Hematol. 2018;93:363–70.
Cited by
12 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献