Abstract
Abstract
Objective
Sunlight and vitamin D intake are considered as essential elements for human health. Insufficient intake of this vitamin is one of the causes of various cancers and some other diseases. The aim of this study was to investigate the relation between bladder, prostate, cervical and ovarian cancers with solar ultraviolet exposure in Iran. In this ecological study, data from 30 provinces were studied and analyzed by correlation and linear regression tests in SPSS software version 22. Physical activity, gender, human development index, lung cancer and altitude were adjusted at population level.
Results
The incidence of bladder cancer in both sexes was inversely related to ultraviolet radiation, but it was significant only in men. Unlike bladder cancer, the incidence of cervical cancer showed a positive relation with ultraviolet radiation. No relation was found between the incidence of prostate and ovarian cancers with ultraviolet radiation. Among the adjusting variables, the incidence of lung cancer (surrogate for smoking) in women had the highest coefficient in the linear regression model.
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference37 articles.
1. Mokarian F, Ramezani MA, Heydari K, Tabatabaeian M, Tavazohi H. Epidemiology and trend of cancer in Isfahan 2005–2010. J Res Med Sci [Internet]. 2011 Sep [cited 2019 Jan 2];16(9):1228–33. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22973394
2. Torre L, Rebecca Siegel AJ. Global Cancer Facts & Fig. 3rd Edition. Am Cancer Soc [Internet]. 2015;(800):1–64. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22019360
3. Siegel RL, Miller KD, Jemal A, Cancer statistics. 2018. CA Cancer J Clin [Internet]. 2018 Jan 1 [cited 2019 Jan 6];68(1):7–30. Available from: https://doi.org/10.3322/caac.21442
4. Beaglehole R, Bonita R, Magnusson R. Global cancer prevention: An important pathway to global health and development. Public Health [Internet]. 2011;125(12):821–31. Available from: https://www.sciencedirect.com/science/article/pii/S0033350611002848
5. Dobruch J, Daneshmand S, Fisch M, Lotan Y, Noon AP, Resnick MJ et al. Gender and Bladder Cancer: A Collaborative Review of Etiology, Biology, and Outcomes. Eur Urol [Internet]. 2016 Feb 1 [cited 2018 Jul 12];69(2):300–10. Available from: https://www.sciencedirect.com/science/article/pii/S0302283815007824