The role of the LRRK2 gene in Parkinsonism
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,Clinical Neurology,Molecular Biology
Link
https://link.springer.com/content/pdf/10.1186/1750-1326-9-47.pdf
Reference125 articles.
1. Kumari U, Tan EK: LRRK2 in Parkinson’s disease: genetic and clinical studies from patients. FEBS J. 2009, 276: 6455-6463. 10.1111/j.1742-4658.2009.07344.x.
2. Bardien S, Lesage S, Brice A, Carr J: Genetic characteristics of leucine-rich repeat kinase 2 (LRRK2) associated Parkinson’s disease. Parkinsonism Relat Disord. 2011, 17: 501-508. 10.1016/j.parkreldis.2010.11.008.
3. Marin I: Ancient origin of the Parkinson disease gene LRRK2. J Mol Evol. 2008, 67: 41-50. 10.1007/s00239-008-9122-4.
4. Gilsbach BK, Kortholt A: Structural biology of the LRRK2 GTPase and kinase domains: implications for regulation. Front Mol Neurosci. 2014, 7: 32-
5. Cardona F, Tormos-Perez M, Perez-Tur J: Structural and functional in silico analysis of LRRK2 missense substitutions. Mol Biol Rep. 2014, 41 (4): 2529-2542. 10.1007/s11033-014-3111-z.
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