Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk-Reference-Cited by-同舟云学术

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Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk

Published:2014-01-04 Issue:1 Volume:9 Page:
ISSN:1750-1326
Container-title:Molecular Neurodegeneration
language:en
Short-container-title:Mol Neurodegeneration

Author:

Tai Leon M,Mehra Shipra,Shete Varsha,Estus Steve,Rebeck G William,Bu Guojun,LaDu Mary Jo

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Molecular Biology

Link

https://link.springer.com/content/pdf/10.1186/1750-1326-9-2.pdf

Reference114 articles.

1. Reitz C, Mayeux R: Use of genetic variation as biomarkers for mild cognitive impairment and progression of mild cognitive impairment to dementia. J Alzheimers Dis. 2010, 19: 229-251.

2. Leoni V: The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer’s disease. Clin Chem Lab Med. 2011, 49: 375-383.

3. Liu CC, Kanekiyo T, Xu H, Bu G: Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nat Rev Neurol. 2013, 9: 106-118. 10.1038/nrneurol.2012.263.

4. Tai LM, Bilousova T, Jungbauer L, Roeske SK, Youmans KL, Yu C, Poon WW, Cornwell LB, Miller CA, Vinters HV, et al: Levels of soluble apolipoprotein E/amyloid-beta (Abeta) complex are reduced and oligomeric Abeta increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples. J Biol Chem. 2013, 288: 5914-5926. 10.1074/jbc.M112.442103.

5. Lue LF, Kuo YM, Roher AE, Brachova L, Shen Y, Sue L, Beach T, Kurth JH, Rydel RE, Rogers J: Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer’s disease. Am J Pathol. 1999, 155: 853-862. 10.1016/S0002-9440(10)65184-X.

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