Author:
Mochizuki Tetsuya,Fujikuni Nobuaki,Nakadoi Koichi,Nakahara Masahiro,Tanabe Kazuaki,Yonehara Shuji,Noriyuki Toshio
Abstract
Abstract
Background
Duodenal carcinoma originating in Brunner’s gland is rare. Herein, we report a case of duodenal carcinoma arising from Brunner’s gland in a 63-year-old man.
Case presentation
On diagnostic imaging, the lesion presented as a non-invasive carcinoma; the patient also had uncontrolled diabetes and liver cirrhosis. Hence, we decided to perform partial duodenectomy to reduce operative stress. Pathological examination revealed that the tumor consisted of tissue from Brunner’s gland. Additionally, the carcinoma cells were strongly positive for Mucin-6 protein, which is an epithelial marker of Brunner’s gland. The patient’s post-operative course was uneventful, and he has been well for 2 years after the surgery.
Conclusions
This a rare case of an adenocarcinoma arising from Brunner’s gland of the duodenum that was resected by duodenectomy.
Publisher
Springer Science and Business Media LLC
Reference14 articles.
1. Cloyd JM, George E, Visser BC. Duodenal adenocarcinoma: advances in diagnosis and surgical management. World J Gastrointest Surg. 2016;8:212–1.
2. Gao YP, Zhu JS, Zheng WJ. Brunner’s gland adenoma of duodenum: a case report and literature review. World J Gastroenterol. 2004;10:2616–7.
3. Peloso A, Vigano J, Vanoli A, Dominioni T, Zonta S, Bugada D, et al. Saving from unnecessary pancreaticoduodenectomy. Brunner's gland hamartoma: Case report on a rare duodenal lesion and exhaustive literature review. Ann Med Surg (Lond). 2017;17:43–9.
4. Kamei K, Yasuda T, Nakai T, Takeyama Y. A case of adenocarcinoma of the duodenum arising from Brunner’s gland. Case Rep Gastroenterol. 2013;7:433–7.
5. Iwamuro M, Kobayashi S, Ohara N, Kawano S, Kawahara Y, Okada H. Adenocarcinoma in situ arising from Brunner’s gland treated by endoscopic mucosal resection. Case Rep Gastrointest Med. 2017;2017:7916976.
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献