Treatment of mouse liver slices with cholestatic hepatotoxicants results in down-regulation of Fxr and its target genes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics
Link
http://link.springer.com/content/pdf/10.1186/1755-8794-6-39.pdf
Reference58 articles.
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2. Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B: Role of bile acids and bile acid receptors in metabolic regulation. Physiol Rev. 2009, 89 (1): 147-191. 10.1152/physrev.00010.2008.
3. Dandel M, Lehmkuhl HB, Knosalla C, Hetzer R: Impact of different long-term maintenance immunosuppressive therapy strategies on patients’ outcome after heart transplantation. Transpl Immunol. 2010, 23 (3): 93-103. 10.1016/j.trim.2010.04.007.
4. Kienhuis AS, Vitins AP, Pennings JL, Pronk TE, Speksnijder EN, Roodbergen M, van Delft JH, Luijten M, van der Ven LT: Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis. Toxicol Lett. 2013, 221 (3): 225-236. 10.1016/j.toxlet.2013.06.236.
5. Abernathy CO, Zimmerman HJ, Ishak KG, Utili R, Gillespie J: Drug-induced cholestasis in the perfused rat liver and its reversal by tauroursodeoxycholate: an ultrastructural study. Proc Soc Exp Biol Med. 1992, 199 (1): 54-58. 10.3181/00379727-199-43328.
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