NH2+ implantations induced superior hemocompatibility of carbon nanotubes

Author:

Guo Meixian,Li Dejun,Zhao Mengli,Zhang Yiteng,Deng Xiangyun,Geng Dongsheng,Li Ruying,Sun Xueliang,Gu Hanqing,Wan Rongxin

Abstract

Abstract NH2 + implantation was performed on multiwalled carbon nanotubes (MWCNTs) prepared by chemical vapor deposition. The hemocompatibility of MWCNTs and NH2 +-implanted MWCNTs was evaluated based on in vitro hemolysis, platelet adhesion, and kinetic-clotting tests. Compared with MWCNTs, NH2 +-implanted MWCNTs displayed more perfect platelets and red blood cells in morphology, lower platelet adhesion rate, lower hemolytic rate, and longer kinetic blood-clotting time. NH2 +-implanted MWCNTs with higher fluency of 1 × 1016 ions/cm2 led to the best thromboresistance, hence desired hemocompatibility. Fourier transfer infrared and X-ray photoelectron spectroscopy analyses showed that NH2 + implantation caused the cleavage of some pendants and the formation of some new N-containing functional groups. These results were responsible for the enhanced hemocompatibility of NH2 +-implanted MWCNTs.

Publisher

Springer Science and Business Media LLC

Subject

Condensed Matter Physics,General Materials Science

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