The androgen receptor can signal through Wnt/β-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens

Author:

Schweizer Liang,Rizzo Cheryl A,Spires Thomas E,Platero J Suso,Wu Qiuyan,Lin Tai-An,Gottardis Marco M,Attar Ricardo M

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology

Reference57 articles.

1. Koivisto P: Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer. Cancer Res. 1997, 57 (2): 314-9.

2. Linja MJ: Amplification and Overexpression of Androgen Receptor Gene in Hormone-Refractory Prostate Cancer. Cancer Res. 2001, 61 (9): 3550-3555.

3. Chen CD: Molecular determinants of resistance to antiandrogen therapy. Nat Med. 2004, 10 (1): 33-39. 10.1038/nm972.

4. Grossmann ME, Huang H, Tindall DJ: Androgen receptor signaling in androgen-refractory prostate cancer. J Natl Cancer Inst. 2001, 93 (22): 1687-97. 10.1093/jnci/93.22.1687.

5. Buchanan G: Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function. Mol Endocrinol. 2001, 15 (1): 46-56. 10.1210/me.15.1.46.

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