Author:
Chen Yongchun,He Dongliang,Yang Tingting,Zhou Hao,Xiang Siyun,Shen Lijun,Wen Jing,Chen Shengcai,Peng Songxu,Gan Yong
Abstract
Abstract
Background
Body composition is a crucial factor associated with the incidence of type 2 diabetes mellitus. However, no study on this relationship has been performed in the Chinese population. This study aimed to investigate the relationship between body composition indicators and risk of type 2 diabetes mellitus among Chinese adults undergoing medical examination.
Methods
Between January 2018 and July 2018, a retrospective cross-sectional study was performed on 3367 (2307 male and 1060 female) participants aged ≥18 years undergoing medical examination in Zhengzhou. Logistic regression analysis was performed to explore the relationship between body composition indicators and risk of type 2 diabetes mellitus. A receiver operating characteristic curve was used to calculate cutoff points and the predictive power of each indicator.
Results
Among the 3367 participants, 12.53% were diagnosed with type 2 diabetes mellitus. Multivariate logistic analysis indicated that male participants (odds ratio [OR] = 1.68, 95% confidence interval [CI]: 1.29–2.19), older participants (OR = 1.05, 95% CI: 1.04–1.06), participants with a waist-to-hip ratio above the reference value (OR = 1.56, 95% CI: 1.18–2.07), participants with body fat percentage above the reference value (OR = 1.62, 95% CI: 1.01–2.68), and participant with a large visceral fat area (OR = 1.01, 95% CI: 1.01–1.02) had a high risk of type 2 diabetes mellitus. Waist-to-hip ratio, body fat percentage, and visceral fat area were the best indicators of type 2 diabetes mellitus (P < 0.001) with cutoff values of 0.90, 25.02%, and 92.00 cm2, respectively.
Conclusion
This study suggests a predictive relationship between type 2 diabetes mellitus and body composition indicators of waist-to-hip ratio, body fat percentage, and visceral fat area, which are valuable for screening diabetes and providing effective health education and behavioral intervention for high-risk populations.
Funder
Postdoctoral Research Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Public Health, Environmental and Occupational Health
Reference28 articles.
1. Evans JM, Newton RW, Ruta DA, et al. Socio-economic status, obesity and prevalence of type 1 and type 2 diabetes mellitus. Diabet Med. 2000;17(6):478–80.
2. Bruno G, Runzo C, Cavallo-Perin P, et al. Incidence of type 1 and type 2 diabetes in adults aged 30-49 years: the population-based registry in the province of Turin, Italy. Diabetes Care. 2005;28(11):2613–9.
3. Holman N, Young B, Gadsby R. Current prevalence of type 1 and type 2 diabetes in adults and children in the UK. Diabet Med. 2015;32(9):1119–20.
4. International Diabetes Federation. IDF Diabetes Atlas. Eight edition. 2017. https://www.idf.org/e-library/epidemiology-research/diabetes-atlas/134-idf-diabetes-atlas-8th-edition.html.
5. Mozaffarian D. Dietary and policy priorities for cardiovascular disease, diabetes, and obesity: a comprehensive review. Circulation. 2016;133(2):187–225.
Cited by
25 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献