Targeted gene sequencing and transcriptome sequencing reveal characteristics of NUP98 rearrangement in pediatric acute myeloid leukemia-Reference-Cited by-同舟云学术

Targeted gene sequencing and transcriptome sequencing reveal characteristics of NUP98 rearrangement in pediatric acute myeloid leukemia

Published:2024-09-02 Issue:1 Volume:29 Page:
ISSN:2047-783X
Container-title:European Journal of Medical Research
language:en
Short-container-title:Eur J Med Res

Author:

Zhang Jing-Ying,Chen Chun-Rong,Qin Jia-Yue,Shen Di-Ying,Liu Li-Xia,Song Hua,Xia Tian,Xu Wei-Qun,Wang Yan,Zhu Feng,Fang Mei-Xin,Shen He-Ping,Liao Chan,Dong Ao,Cao Shan-Bo,Tang Yong-Min,Xu Xiao-Jun

Funder

Pediatric Leukemia Diagnosis and Therapeutic Technology Research Center of Zhejiang Province

Zhejiang University Special Funds Project of Fundamental Research Funds

Natural Science Foundation of Zhejiang Province, China

Publisher

Springer Science and Business Media LLC

Link

https://link.springer.com/content/pdf/10.1186/s40001-024-02042-9.pdf

Reference37 articles.

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2. Struski S, Lagarde S, Bories P, et al. NUP98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis. Leukemia. 2017;31(3):565–72.

3. Michmerhuizen NL, Klco JM, Mullighan CG. Mechanistic insights and potential therapeutic approaches for NUP98-rearranged hematologic malignancies. Blood. 2020;136(20):2275–89.

4. Iacobucci I, Wen J, Meggendorfer M, et al. Genomic subtyping and therapeutic targeting of acute erythroleukemia. Nat Genet. 2019;51(4):694–704.

5. Hollink IH, van den Heuvel-Eibrink MM, Arentsen-Peters ST, et al. NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern. Blood. 2011;118(13):3645–56.