Author:
Xu Mingjie,Liu Fang,Zhao Qianqian,Zhou Yunying,Zhuang Yuanmei,Ji Mingyu
Abstract
Abstract
Background
The updated estimates of hepatitis C virus (HCV) seroprevalence are critical for developing strategies to manage or eliminate HCV infection.
Methods
A comprehensive study on HCV seroprevalence was conducted among 365,210 patients at Jinan Central Hospital, China, from 2008 to 2020. The patients were tested for anti-HCV, HCV core antigen, hepatitis B surface antigen, syphilis antibody, human immunodeficiency virus antigen + antibody, antihepatitis A virus IgM, and antihepatitis E virus IgM.
Results
HCV seroprevalence was 0.79% and was related to age. HCV seropositivity was lower in children (aged < 18 years) than in adults (aged ≥ 18 years) (0.15% vs. 0.81%). High HCV prevalence was reported in adults aged ≥ 41 years, and HCV seropositivity in those aged 41–80 years accounted for 74.56% of all seropositive individuals. Notably, the rate of HCV–HIV coinfection was 0. HCV seroprevalence was considerably higher in patients at the Kidney Disease Unit and Dialysis Department than in those at other departments (inpatient or outpatient).
Conclusions
HCV seroprevalence was lower in Jinan region but higher in patients at the Kidney Disease Unit and Dialysis Department, especially in those undergoing hemodialysis.
Funder
Jinan Postdoctoral Innovation Project Second-Class Funding
Jinan Central Hospital 2020 High-level Subject Cultivation Program Youth Project
The second batch of science and technology plan projects of Jinan Municipal Health Commission in 2020
Academic Promotion Programme of Shandong First Medical University
Shandong Key Research and Development Fund
Jinan clinical medical science and technology innovation Fund
Publisher
Springer Science and Business Media LLC
Cited by
1 articles.
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