Author:
Yuan F.,Chen J.,Liu F.,Dang Y. C.,Kong Q. T.,Sang H.
Abstract
Abstract
Background
Mucormycosis is a rare fungal infection occurring chiefly in the lung or the rhino-orbital-cerebral compartment, particularly in patients with immunodeficiency or diabetes mellitus. Among Mucorales fungi, Rhizopus spp. are the most common cause of mucormycosis.
Case presentation
We report a case of pulmonary mucormycosis caused by Rhizopus microsporus in a young patient with diabetes but no other apparent risk factors. The diagnosis mainly relied on clinical manifestation, positive pulmonary tissue biopsy, and fungal culture. The patient was successfully treated with posaconazole oral suspension and remains asymptomatic at one-year follow-up.
Conclusions
Pulmonary mucormycosis is a life-threatening condition and posaconazole is an effective treatment for pulmonary mucormycosis caused by Rhizopus microspores.
Publisher
Springer Science and Business Media LLC
Reference9 articles.
1. Corzo-León DE, Chora-Hernández LD, Walsh TJ, et al. Diabetes mellitus as the major risk factor for mucormycosis in Mexico: epidemiology, diagnosis, and outcomes of reported cases. Med Mycol. 2018;56(1):29–43. https://doi.org/10.1093/mmy/myx017.
2. Bitar D, Lortholary O, Le Strat Y, et al. Population-based analysis of invasive fungal infections, France, 2001–2010. Emerg Infect Dis. 2014;20:1149–55. https://doi.org/10.3201/eid2007.140087.
3. Lelievre L, Garcia-Hermoso D, French Mycosis Study Group, et al. Posttraumatic mucormycosis: a nationwide study in France and review of the literature. Medicine. 2014;93(24):395–404. https://doi.org/10.1097/MD.0000000000000221.
4. Roden MM, Zaoutis TE, Buchanan WL, et al. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis. 2005;41:634–53. https://doi.org/10.1086/432579.
5. National Committee for Clinical Laboratory Standards. Reference method for broth dilution antifungal susceptibility testing of filamentous fungi. Approved standard. NCCLS document M38-A. Villanova: Clinical and Laboratory Standards Institute; 2002.
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