Author:
Ullah Amir,Huang Yiyi,Zhao Kening,Hua Yuneng,Ullah Shafi,Rahman Mujeeb ur,Wang Jingyu,Wang Qian,Hu Xiumei,Zheng Lei
Abstract
AbstractExtracellular vesicles (EVs) are a heterogeneous group of lipid membrane-enclosed compartments that contain different biomolecules and are released by almost all living cells, including fungal genera. Fungal EVs contain multiple bioactive components that perform various biological functions, such as stimulation of the host immune system, transport of virulence factors, induction of biofilm formation, and mediation of host–pathogen interactions. In this review, we summarize the current knowledge on EVs of human pathogenic fungi, mainly focusing on their biogenesis, composition, and biological effects. We also discuss the potential markers and therapeutic applications of fungal EVs.
Funder
National Natural Science Foundation of China
China Postdoctoral Science Foundation
Basic and Applied Basic Research Foundation of Guangdong Province
Guangzhou Science and Technology Plan Project-Basic and Applied Basic Research Projects
the President Foundation of Nanfang Hospital Southern Medical University
National Science Fund for Distinguished Young Scholars
Clinical research subject of Guangdong Medical Association
Publisher
Springer Science and Business Media LLC
Subject
Microbiology (medical),Microbiology
Cited by
4 articles.
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