Pyroglutamate and Isoaspartate modified Amyloid-Beta in ageing and Alzheimer’s disease-Reference-Cited by-同舟云学术

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Pyroglutamate and Isoaspartate modified Amyloid-Beta in ageing and Alzheimer’s disease

Published:2018-01-03 Issue:1 Volume:6 Page:
ISSN:2051-5960
Container-title:Acta Neuropathologica Communications
language:en
Short-container-title:acta neuropathol commun

Author:

Moro Maria Luisa,Phillips Andrew Stephen,Gaimster Katie,Paul Christian,Mudher Amritpal,Nicoll James A. R.,Boche Delphine

Funder

Marie Curie Intra European Fellowship within the 7th European Community Framework

Alzheimer’s Research UK

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Pathology and Forensic Medicine

Link

http://link.springer.com/content/pdf/10.1186/s40478-017-0505-x.pdf

Reference46 articles.

1. Aho L, Pikkarainen M, Hiltunen M, Leinonen V, Alafuzoff I (2010) Immunohistochemical visualization of amyloid-beta protein precursor and amyloid-beta in extra- and intracellular compartments in the human brain. J Alzheimers Dis 20:1015–1028. https://doi.org/10.3233/JAD-2010-091681

2. Alafuzoff I, Pikkarainen M, Arzberger T, Thal DR, Al-Sarraj S, Bell J, Bodi I, Budka H, Capetillo-Zarate E, Ferrer I et al (2008) Inter-laboratory comparison of neuropathological assessments of beta-amyloid protein: a study of the BrainNet Europe consortium. Acta Neuropathol 115:533–546. https://doi.org/10.1007/s00401-008-0358-2

3. Fossati S, Todd K, Sotolongo K, Ghiso J, Rostagno A (2013) Differential contribution of isoaspartate post-translational modifications to the fibrillization and toxic properties of amyloid beta and the Asn23 Iowa mutation. Biochem J 456:347–360. https://doi.org/10.1042/BJ20130652

4. Frost JL, Liu B, Rahfeld JU, Kleinschmidt M, O'Nuallain B, Le KX, Lues I, Caldarone BJ, Schilling S, Demuth HU et al (2015) An anti-pyroglutamate-3 Abeta vaccine reduces plaques and improves cognition in APPswe/PS1DeltaE9 mice. Neurobiol Aging 36:3187–3199. https://doi.org/10.1016/j.neurobiolaging.2015.08.021

5. Gouras GK, Tsai J, Naslund J, Vincent B, Edgar M, Checler F, Greenfield JP, Haroutunian V, Buxbaum JD, Xu H et al (2000) Intraneuronal Abeta42 accumulation in human brain. Am J Pathol 156:15–20

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