Deposition of mutant ubiquitin in parkinsonism–dementia complex of Guam-Reference-Cited by-同舟云学术

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Deposition of mutant ubiquitin in parkinsonism–dementia complex of Guam

Published:2017-11-09 Issue:1 Volume:5 Page:
ISSN:2051-5960
Container-title:Acta Neuropathologica Communications
language:en
Short-container-title:acta neuropathol commun

Author:

Verheijen Bert M.,Hashimoto Tomoyo,Oyanagi Kiyomitsu,van Leeuwen Fred W.

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Pathology and Forensic Medicine

Link

http://link.springer.com/content/pdf/10.1186/s40478-017-0490-0.pdf

Reference13 articles.

1. de Pril R, Fischer DF, Maat-Schieman MLC, Hobo B, De Vos RAI, Brunt ER, Hol EM, Roos RAC, Van Leeuwen FW (2004) Accumulation of aberrant ubiquitin induces aggregate formation and cell death in polyglutamine diseases. Hum Mol Genet 13:1803–1813. doi: 10.1093/hmg/ddh188

2. Dennissen FJA, Kholod N, Hermes DJHP, Kemmerling N, Steinbusch HWM, Dantuma NP, Van Leeuwen FW (2011) Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3). FEBS Lett 585:2568–2574. doi: 10.1016/j.febslet.2011.06.037

3. Fischer DF, De Vos RAI, Van Dijk R, De Vrij FMS, Proper EA, Sonnemans MAF, Verhage MC, Sluijs JA, Hobo B, Zouambia M, Steur ENHJ, Kamphorst W, Hol EM, Van Leeuwen FW (2003) Disease-specific accumulation of mutant ubiquitin as a marker for proteasomal dysfunction in the brain. FASEB J 17:2014–2024. doi: 10.1096/fj.03-0205com

4. Fischer DF, Van Dijk R, van Tijn P, Hobo B, Verhage MC, van der Schors RC, Li KW, van Minnen J, Hol EM, Van Leeuwen FW (2009) Long-term proteasome dysfunction in the mouse brain by expression of aberrant ubiquitin. Neurobiol Aging 30:847–863. doi: 10.1016/j.neurobiolaging.2008.06.009

5. Hasegawa M, Arai T, Akiyama H, Nonaka T, Mori H, Hashimoto T, Yamazaki M, Oyanagi K (2007) TDP-43 is deposited in the Guam parkinsonism-dementia complex brains. Brain 130:1386–1394. doi: 10.1093/brain/awm065

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