Abundant kif21b is associated with accelerated progression in neurodegenerative diseases

Author:

Kreft Karim L,van Meurs Marjan,Wierenga-Wolf Annet F,Melief Marie-Jose,van Strien Miriam E,Hol Elly M,Oostra Ben A,Laman Jon D,Hintzen Rogier Q

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Pathology and Forensic Medicine

Reference37 articles.

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2. Calabrese M, De Stefano N, Atzori M, Bernardi V, Mattisi I, Barachino L, Morra A, Rinaldi L, Romualdi C, Perini P, Battistin L, Gallo P: Detection of cortical inflammatory lesions by double inversion recovery magnetic resonance imaging in patients with multiple sclerosis. Arch Neurol 2007, 64: 1416–1422. doi:64/10/1416; 10.1001/archneur.64.10.1416 10.1001/archneur.64.10.1416

3. Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z, Freeman C, Hunt SE, Edkins S, Gray E, Booth DR, Potter SC, Goris A, Band G, Oturai AB, Strange A, Saarela J, Bellenguez C, Fontaine B, Gillman M, Hemmer B, Gwilliam R, Zipp F, Jayakumar A, Martin R, Leslie S, Hawkins S, et al.: Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 2011, 476: 214–219. doi:nature10251 10.1038/nature10251 10.1038/nature10251

4. McCauley JL, Zuvich RL, Beecham AL, De Jager PL, Konidari I, Whitehead PL, Aubin C, Ban M, Pobywajlo S, Briskin R, Romano S, Aggarwal NT, Piccio L, McArdle WL, Strachan DP, Evans D, Cross AH, Cree B, Rioux JD, Barcellos LF, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL: Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci. Hum Mol Genet 2010, 19: 953–962. doi:ddp542; 10.1093/hmg/ddp542 10.1093/hmg/ddp542

5. Marszalek JR, Weiner JA, Farlow SJ, Chun J, Goldstein LS: Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B. J Cell Biol 1999, 145: 469–479. 10.1083/jcb.145.3.469

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