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TDP-43 pathology in the basal forebrain and hypothalamus of patients with amyotrophic lateral sclerosis

  • Published:2014-12 Issue:1 Volume:2 Page:
  • ISSN:2051-5960
  • Container-title:Acta Neuropathologica Communications
  • language:en
  • Short-container-title:acta neuropathol commun

Author:

Cykowski Matthew D,Takei Hidehiro,Schulz Paul E,Appel Stanley H,Powell Suzanne Z

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology (clinical),Pathology and Forensic Medicine

Reference47 articles.

1. Ravits J, Appel S, Baloh RH, Barohn R, Brooks BR, Elman L, Floeter MK, Henderson C, Lomen-Hoerth C, Macklis JD, McCluskey L, Mitsumoto H, Przedborski S, Rothstein J, Trojanowski JQ, van den Berg LH, Ringel S: Deciphering amyotrophic lateral sclerosis: what phenotype, neuropathology and genetics are telling us about pathogenesis. Amyotroph Lateral Scler Frontotemporal Degener 2013, 14(Suppl 1):5–18. doi:10.3109/21678421.2013.778548 10.3109/21678421.2013.778548

2. Al-Chalabi A, Jones A, Troakes C, King A, Al-Sarraj S, van den Berg LH: The genetics and neuropathology of amyotrophic lateral sclerosis. Acta Neuropathol 2012, 124(3):339–352. doi:10.1007/s00401–012–1022–4 10.1007/s00401-012-1022-4

3. Geser F, Brandmeir NJ, Kwong LK, Martinez-Lage M, Elman L, McCluskey L, Xie SX, Lee VM, Trojanowski JQ: Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in amyotrophic lateral sclerosis. Arch Neurol 2008, 65(5):636–641. doi:10.1001/archneur.65.5.636 10.1001/archneur.65.5.636

4. Zhang YJ, Xu YF, Cook C, Gendron TF, Roettges P, Link CD, Lin WL, Tong J, Castanedes-Casey M, Ash P, Gass J, Rangachari V, Buratti E, Baralle F, Golde TE, Dickson DW, Petrucelli L: Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity. Proc Natl Acad Sci U S A 2009, 106(18):7607–7612. doi:10.1073/pnas.0900688106 10.1073/pnas.0900688106

5. Ringholz GM, Appel SH, Bradshaw M, Cooke NA, Mosnik DM, Schulz PE: Prevalence and patterns of cognitive impairment in sporadic ALS. Neurology 2005, 65(4):586–590. doi:10.1212/01.wnl.0000172911.39167.b6 10.1212/01.wnl.0000172911.39167.b6
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