In silicotoxicology models and databases as FDA Critical Path Initiative toolkits

Author:

Valerio Luis G

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Genetics,Molecular Biology,Molecular Medicine

Reference37 articles.

1. EU: Regulation (EC) No 1907/2006 of The European Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94, as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. OJEU. 2006, L396: 1-843. (EC 1907/2006)

2. NRC: Toxicity Testing in the 21st Century: A Vision and a Strategy. 2007, National Academy Press, Washington, DC

3. FDA: Critical Path Initiative. 2010, US Department of Health and Human Services, Rockville, MD, (accessed 15th June, 2010), [ http://www.fda.gov/ScienceResearch/SpecialTopics/CriticalPathInitiative/default.htm ]

4. FDA: Challenge and opportunity on the critical path to new medical products. 2004, US Department of Health and Human Services, US Food and Drug Administration, Rockville, MD, [ http://www.fda.gov/ScienceResearch/SpecialTopics/CriticalPathInitiative/CriticalPathOpportunitiesReports/ucm()77262.htm ]

5. Yang C, Valerio LG, Arvidson KB: Computational toxicology approaches at the US Food and Drug Administration. Altern Lab Anim. 2009, 37: 523-531.

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