Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-β1b (MIRACLE trial): study protocol for a randomized controlled trial-Reference-Cited by-同舟云学术

Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-β1b (MIRACLE trial): study protocol for a randomized controlled trial

Published:2018-01-30 Issue:1 Volume:19 Page:
ISSN:1745-6215
Container-title:Trials
language:en
Short-container-title:Trials

Author:

Arabi Yaseen M., ,Alothman Adel,Balkhy Hanan H.,Al-Dawood Abdulaziz,AlJohani Sameera,Al Harbi Shmeylan,Kojan Suleiman,Al Jeraisy Majed,Deeb Ahmad M.,Assiri Abdullah M.,Al-Hameed Fahad,AlSaedi Asim,Mandourah Yasser,Almekhlafi Ghaleb A.,Sherbeeni Nisreen Murad,Elzein Fatehi Elnour,Memon Javed,Taha Yusri,Almotairi Abdullah,Maghrabi Khalid A.,Qushmaq Ismael,Al Bshabshe Ali,Kharaba Ayman,Shalhoub Sarah,Jose Jesna,Fowler Robert A.,Hayden Frederick G.,Hussein Mohamed A.

Funder

king Abdullah International Medical Research Center

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Medicine (miscellaneous)

Link

http://link.springer.com/content/pdf/10.1186/s13063-017-2427-0.pdf

Reference39 articles.

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2. Arabi YM, Balkhy HH, Hayden FG, Bouchama A, Luke T, Baillie JK, Al-Omari A, Hajeer AH, Senga M, Denison MR, et al. Middle East Respiratory Syndrome. N Engl J Med. 2017;376(6):584–94.

3. Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med. 2012;367(19):1814–20.

4. Mo Y, Fisher D. A review of treatment modalities for Middle East Respiratory Syndrome. J Antimicrob Chemother. 2016;71(12):3340–50.

5. Falzarano D, de Wit E, Rasmussen AL, Feldmann F, Okumura A, Scott DP, Brining D, Bushmaker T, Martellaro C, Baseler L, et al. Treatment with interferon-alpha2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques. Nat Med. 2013;19(10):1313–7.

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